donderdag 17 november 2011

Klebsiella in verband gebracht met de ziekte van Bechterev en de ziekte van Crohn

Klebsiella Bacteria Studied in Relation to Colic and Crohn's

A new study published in the Journal of Pediatrics, by J Marc Rhoads, MD, and colleagues has identified Klebsiella bacterium as a possible suspect in colic in babies.  
Klebsiella are a common bacteria, but in a study of 36 babies, half of whom were colicky, only those with colic were found to have Klebsiella in their intestines.  In the small study non colicky babies had more bacteria in their instestines, but not Klebsiella
Klebsiella has been discussed in relation to Crohn's disease as well as ankylosing spondylitis.  Ankylosing spondylitis is a chronic, inflammatory arthritis and autoimmune disease that many Crohn's patients have and an ancillary disease which shares some treatments with Crohn's such as immunosupressents and anti-TNF drugs.
According to the study, there may be some possibility of treating colic with probiotics, the idea being that if you populate the digestive tract with good bacteria, it will force out the inflammation causing klebsiella.
This extract from the European Journal of Gastroenterology & Hepatology which discusses the role of klebsiella bacteria in Crohn's and Ankylosing Spondylitis mentions  that the role of this bacteria might explain why some patients get relief from a low starch and lactose free diet.  Here is a quote from the abstract:
A link exists between high dietary starch intake and the growth of intestinal microflora, involving especiallyKlebsiella microbes. Increased exposure to Klebsiella in the gut as the result of high starch intake would lead to high production of anti Klebsiella antibodies as well as auto antibodies to the cross-reactive self-antigens with the resultant inflammation at the pathological sites. Eradication of these microbes from the gut in patients with Crohn's disease with the use of low-starch diet and antibacterial agents as well as immunomodulatory measures could be beneficial in the management of this disease.
Klebsiella is a lactose eating bacteria, so it makes sense that it you don't give it the food it likes it could lower the concentration of the bacteria in the colon.  It seems to make sense to me as well, that taking strong probiotics would also force out the other bacterias and replace the flora with the bacterias that don't cause inflammation.  This actually makes a great case for the Specific Carbohydrate diet, and Makers Diet plans which many IBD patients find work for them.
Here is a link to the Probiotic I personally take.  The Primadophilus Reuteri is one of the strains that has been shown to help IBD, and these pearls from Nature's Way do not need refrigeration.
Reuteri is an unique lactobacillus is naturally found in human breast milk, and is one of the first defenses a nursing mother passes to her child. Studies show that moms who take Rueteri during the last 4 weeks of pregnancy have babies with less excema, also helps prevent Asthma, respirtory infections and colic in the baby.

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