Dr. Mccandless over LDN bij autisme

Deze reportage van dr. McCandless over de behandeling van autisme met o.a. het gebruik van LDN daarbij is zeer de moeite waard om te beluisteren. Het duurt even voordat de film geladen is maar het is beslist de moeite waard erop te wachten:

http://www.youtube.com/watch?v=30EGZzgKID4

http://www.youtube.com/watch?v=LJGatrZ9smo

Kan de toename in autisme in verband staan met het gebruik van progestagenen

Urgent need for progress in autism Could the increase in autism relate to use of progestin contraceptives, as well as to other environmental factors?

• Ellen CG Grant, Physician and Medical Gynaecologist

Kingston-upon-Thames, KT2 7JU

The prevalence of autism increased by 300% between 1987 and 1998 in California but the increase in the prevalence of cerebral palsy, epilepsy and mental retardation was only 3%. In the UK about one in 87 children are now autistic.1

What has changed over the past decade apart from a large increase in childhood vaccinations? We now have up to 3 successive generations of women who have used hormonal contraceptives with increasingly longer use from younger ages before first full time pregnancies (which increases breast cancer risks).

Such hormone use lowers white cell zinc and raises copper levels leading to impaired superoxide dismutase (SOD) function and reduced ability to deal with oxidative stress. Adequate zinc levels are needed for DNA repair. Vitamin B6 , B12 and folic acid levels and omega-3 and omega-6 essential fatty acid (EFA) deficiencies are common. I have routinely investigated the biochemistry of hundreds of women with histories of unexplained infertility and recurrent miscarriages. Most preconception patients are past hormone takers, with 50% longer takers for 5 years, and most have mineral deficiencies and poor SOD activity.

McLaren-Howard has presented data showing that women who ever took hormones had more DNA adducts than never takers. Of 356 women who had used oral contraceptives or HRT, 12.4% had adducts to nickel and 8.7% to Lindane compared with 7.1% and 3.8% of 182 never takers.2 He also compared 27 patients with cancer with 27 age and sex matched controls. 18.5% of cancer patients had DNA adducts to malondialdehyde (from lipid oxidation) and 18.5% had adducts to nickel compared with 0% and 3.7% of controls respectively.2

McLaren-Howard's routine analyses of blood from 61 autistic children found deficiencies of zinc, magnesium, chromium, selenium, manganese, molybdenum, and/or B vitamins. Such deficiencies can impair EFA pathways. In addition, 26% (16) of the children had DNA-adducts to malondialdehyde in their leucocytes, 20% (12) to cadmium, 15% (9) to nickel and one child had DNA-adducts to lead.3 A simple non-invasive sweat test shows that children with learning problems usually suffer from zinc deficiency and have higher levels of common toxic metals. Zinc deficiency increases food and chemical allergies and decreases food absorption.

Experimentally, higher doses of chlormadione and megestrol (progestins without oestrogenic or androgenic activity) increased sister chromatid exchanges and chromosomal aberrations. In vitro studies show the generation of free oxygen radicals by progestins to be responsible for genotoxic damage.4

Could longer progestin use cause more maternal genotoxic damage which in turn increases the susceptibility of children to develop autism? In a 2010 exploratory study children with autism were more likely to have mitochondrial dysfunction, mitochondrial DNA over-replication, and mitochondrial DNA deletions than typically developing children.5

Children who are susceptible to becoming autistic, or who seem apparently healthy but die from common infections, are not easily identified by epidemiological means. Perturbations of basic cell chemistry in mothers and children should be investigated and treated. Brain function is particularly vulnerable to damage by toxins and by deficiencies of zinc and essential fatty acids.

1 Downing D. Autism: are we entering the final straight? In memory of Bernard Rimland. JNEM 2007;16:3,173-180.

2 McLaren Howard J. The Detection of DNA Adducts (Risk Factors for DNA Damage). A Method for Genomic DNA, the Results and Some Effects of Nutritional Intervention. J. Nutr. & Env. Medicine. 2002; 12: 19-31. Also Essential nutrients, anti-nutrients, oestrogenic pesticides, toxic metals and DNA-adducts. Further results presented at the British Society for Ecological Medicine conference Progesterone and Breast Cancer. London November 2006

3 Grant ECG. McLaren-Howard J. Re: The effects of toxic metals in autistic children. http://bmj.com/cgi/eletters/329/7466/588-b#74117, 13 Sep 2004

4 Siddique YH, Beg T, Afzal M. Antigenotoxic effects of ascorbic acid against megestrol acetate-induced genotoxicity in mice. Hum Exp Toxicol. 2005 Mar;24(3):121-7.

5 Giulivi C, Zhang YF, Omanska-Klusek A, Ross-Inta C, Wong S, Hertz- Picciotto I, Tassone F, Pessah IN. Mitochondrial dysfunction in autism. JAMA 2010 Dec 1;304(21):2389-96.

Competing interests: None declared

Kamelenmelk, gezond of alleen maar een hype?

Camel Milk: Healing or Hype?

 AUTISM NEWS BY JULIE MATTHEWS 24 COMMENTS

Drink camel’s milk?  Really?  And, for those who cannot drink the milk from a goat or cow, is it possible camel’s might be for you?

As a nutritionist for children with autism for 10 years, my research and clinical experience indicate that most children with autism cannot adequately tolerate dairy. Particularly, their bodies have challenges digesting the protein casein.  Even when milk is raw and contains A2 beta-casein (not A1), experience shows that most children do not tolerate it.

So, imagine my delight (and skepticism) when parents approached me and shared personal stories about the healing properties of camel milk, and how its fundamentally different than any other milk on the planet.

As I began to research it for myself, I heard from autism parents who told me that camel milk has helped their children tremendously, with not adverse reactions to this “dairy.” (Thank you Randi, Jessica and Nicole – I learn so much from you parents on the front lines.)

Camel milk may seem obscure, but the more I research and read personal anecdotes from parents and clinicians the world over, the more amazing I think it may actually be at helping recover kids with autism – and many others with gut issues, immune system challenges, nutrient deficiencies, and more!

If you’re following the GAPS Diet, gluten-free casein-free, or any healing food strategy intended to improve the body’s chemistry and functioning, you should be curious about camel milk.

Camel Milk’s Healing Power

Research and experience from an increasing number of people around the world demonstrate that camel milk facilitates healing in our bodies. Camel milk has many unique and amazing properties.

Here’s some quick research:

• Camel milk has been shown to heal food allergies (1) and gut problems. The antibodies and immune properties of camel’s milk contribute to its wonderful viral and bacterial fighting abilities.
• It is particularly helpful in addressing immune system dysregulation in various forms.  Camel milk can support and help people with autoimmune conditions, including autism, heal.
• A research study by Dr. Reuven Yagil (2005) shows camel milk has positive results in children with autism. (2)
• Camel milk contains insulin and is effective in diabetes (3), including gestational diabetes (4)^.

Since children with autism routinely have immune system challenges: inability to fight bacterial, viral and other infections, and states of chronic inflammation, allergy, and autoimmunity, camel milk has promising health and healing benefits.

Camel herders and indigenous cultures have known about the power of camel milk for a long time.  To this day, Bedouin parents send their children to drink camel milk for a couple weeks in their childhood, as they know that it sets up a strong immune system for life.  Dr. Weston A. Price observed their dental health (and therefore physical health) was excellent stating, “The Arabs in several districts use camels’ milk extensively.  It is nutritious, and in much of the desert country constitutes the mainstay of the nomads for months at a time.” (5)

Camels are built differently than any other animal. Camels are not ruminants but are Tylopodes and have three stomachs, but they do ruminate.  They can survive in incredibly harsh climates, and are able to live without water for 30 days at a time (even with little food), while still producing high quality milk.  Imagine that!  A large part of camel milk’s healing power stems from the unique and hardy immune system of camels, it’s unlike any other mammal.

Camel Milk: Highly Nutritious with Unique Casein

Camel milk is highly nutritious. The milk contains only 2% fat (I’m not a fan of a low-fat, but these are the facts).  The fat molecules are joined to protein, so there is no stress on the liver to process it.  Higher is some nutrients and lower in others—camel milk is rich in vitamin C (5x that of cow’s milk), iron (10x) and calcium. The fat profile of camel milk varies in a “rich diet” (domesticated camels) versus the diet camels eat in the desert – but generally it’s high in polyunsaturated fatty acids, with a higher ratio of omega 3 to omega 6 compared with cow’s milk.

Camel milk is considered a complete food and can be consumed exclusively while meeting all nutritional requirements.  Camel milk is most frequently consumed raw and unpasteurized, because the raw milk contains the most nutritional and immune properties.  Only when the quality and safety of the milk is in question would someone pasteurize it.

Camel’s milk contains no beta-lactoglobulin and a “new” beta-casein (6). Therefore it is not reactive to children with autism and even non-allergenic to those with even the most sensitive allergy to milk and casein. One study found Camel’s milk was also not recognized from circulating IgEs from a child specifically allergic to ewe’s milk.(7) Children with severe food allergies react well to the milk, and astonishingly, fully recover from their allergies including to other foods (1).

Casein molecules are actually micelles and camel micelles have been found to be larger in size (15 nm) than those of cow milk or human milk. (8).  Camel milk has a lower pH than other milk, so that upon entering the stomach the casein micelles do not breakdown into casein and whey and therefore do not break into casomorphins.  Casomorphin creation from cow milk consumption is a common problem in autism that increases autistic symptoms.

Camel Milk: Immune Benefits

Camel milk has an amazing immune profile.

The immunoglobulins (Igs) and protective proteins in camel milk contribute to camel milk’s incredible infection fighting and eradication capacity.  Camel Igs (which exist in the milk) are able to penetrate into tissues and cells that human Igs were unable to.  Therefore, they are able to get into the kidney or inside a cell, where they are also able to completely neutralize the enzyme activity of an infectious agent such as a bacteria or virus.

Camel Immunoglobulins

Camel milk also contains immunoglobulins (Igs) that are special in camels, including unique subclasses IgG2 and IgG3.   The Igs are the same structure as human immunoglobulins but only one-tenth the size.  Being so small, they can penetrate into tissues and organs to fight infection and aid repair, where human antibodies cannot.

Camel antibodies have superior antibacterial and antiviral properties.  As stated in Dr. Reuven Yagil’s autoimmune paper, “conventional antibodies rarely show a complete neutralizing activity against enzyme antigens, but camel IgG has a full neutralizing activity against tetanus toxin as it enters the enzymes structure.” (9).  Viruses can also be neutralized by knocking out their enzyme activity, and studies show the camel antibody is an effective inhibitor against hepatitis C enzyme system (10).

In a study on camel milk for autism, the author compares camel milk to intravenous immunoglobulin therapy that acts as a natural immunoglobulin therapy, whose effects continue after the therapy is stopped, because of the immune rehabilitating action.

Camel Immune Protective Proteins

Camel milk contains the following immune proteins (often in higher qualities than other milk):

• Peptidoglycan Recognition Protein, PGRP is very high in camel milk. It stimulates the host’s immune response and has antimicrobial activity.  It even appears to have an effect on breast cancer in studies.
• Lactoferrin is also in higher concentrations in camel milk, more than cows and goats.  Lactoferrin prevents microbial overgrowth and invading pathogens.  Lactoperoxidase, has bactericidal activity on gram-negative bacterial like Escherichia coli (E. coli), Salmonella, and, Pseudomonas, and has antitumor activity.
• Lysozyme is an enzyme that is part of the innate immune system that targets gram-positive bacteria.  N-acetyl-beta-D-glucosamidase (NAGase) found in similar quantities in human milk has antibacterial activity.

Autoimmunity

One theory about autoimmune disease is that the body attacks itself because it’s trying (in vain) to get at the bacteria buried in the intestinal tissue.  Camel milk’s antibacterial activities and the special immune response allow for their penetration into the intestinal tissues when the “quiet” bacteria turn pathogenic.  Because the antibodies are able to get into the affected tissue to attack the infectious agent (for example the saprophyte bacteria found in Crohn’s disease), camel milk can help someone heal in ways not seen through any other intervention – dietary or otherwise.

Autism and Beyond

Dr. Yagil says that “camel milk does not contain the two caseins that lead to the autism symptoms when drinking cow milk.  Therefore camel milk can safely be drunk by autistic children.” The results published in a paper on camel milk for autism were very positive, especially for younger children that “showed an apparent complete recovery from autism after strict removal of cow’s milk”. (2) Regarding the results seen with autism, Dr. Yagil explains, “it is NOT only a case of repressing the clinical signs but a rehabilitation of the immune system.  Therefore the kids completely recover. “

Since camel milk is nourishing and easy to digest, it does not trigger allergenic or opiate responses, and helps heal the gut and infections, protecting and enhancing the immune system.

Considering the vast qualities of camel milk, there’s seems no limit to the range of maladies that it many help address.  The positive reports from parents are exciting – camel milk holds great promise, and future study and clinical experience will be valuable. From parents to professionals like Dr. Yagil, I am intrigued and enthused about the value and healing properties of camel milk for people with a wide variety health conditions.

Camel milk would be a wonderful addition to people on special diets such as GAPS. I’m drinking it, and so is my baby.

References

1. Yosef Shabo MD, Reuben Barzel MD, Mark Margoulis MD and Reuven Yagil DVM. Camel milk for food allergies in children. IMAJ 2005;7:796–798

2. Yosef Shabo, PhD, MD and Reuven Yagil, DVM. Etiology of autism and camel milk as therapy. 
International Journal on Disability and Human Development 2005;4(2):67-70

3 
 R.P. Agrawal, R. Beniwal, S. Sharma, D.K. Kochar, F.C. Tuteja, S.K.Ghorui and M.S. Sahani. Effect of raw camel milk in type 1 diabetic patients: 1 year randomised study. 
Journal of Camel Practice and Research 12(1), p. 27-35, 2005

4. Dr. Reuven Yagil, video presentation at the symposium of “Gastro-Intestinal and Immunological diseases and how they relate to Camel Milk.” February 9, 2011.

5. Price, Weston A, Nutrition and Physical Degeneration. The Price-Pottenger Nutrition Foundation, La Mesa, CA, 2008.

6 Obaid Ullah Beg, Hedvig von Bahr-Lindström, Zafar H. Zaidi, Hans Jörnvall. Characterization of a camel milk protein rich in proline identifies a new β-casein fragment. Regulatory Peptides, Volume 15, Issue 1, August 1986, Pages 55-61.

7. P. Restani, A. Gaiaschi, A. Plebani, B. Beretta, G. Cavagni, A. Fiocchi, C. PoiesiI, T. Velona, A.G. Ubazio and C.L.. Cross-Reactivity between milk proteins from different animal species. Clinical and Experimental Allergy, 1999, Volume 29, 997-1004.

8 Kappeler S., Farah Z., Puhan Z. Sequence analysis of Camelus dromedarius milk caseins. Journal of Dairy Research (1998) 65 209–222.

9 Prof Reuven Yagil, Paper, “Camel Milk and Autoimmune Diseases: Historical Medicine.” 2004.

10 Martin, F., Volpari, C., Steinkuhler, C., Dimas, N., Burnetti, M.,Biasiol, G., Altamura S., Cortese, R., De Francesco, R., Sollazzo, M. Affinity selection of a camelized V (H) domain antibody inhibitor of hepatitis Cvirus NS3 protease. Protein Engineering. (1997) 10: 607-614.

De gevaren van koemelk; ook van rauwe koemelk

De gevaren van koemelk


Koemelk is een product dat door miljarden mensen wordt gebruikt, maar toch zijn er samenlevingen die geen melk gebruiken. De Eskimo's, de Bantoes, veel mensen in Azixeb en de Indianen van Noord en Zuid Amerika. In de samenlevingen waar ze geen melk gebruiken kun je geen MS vinden. In veel van deze samenlevingen waar men traditioneel voedsel eet, komt ook veel minder kanker voor.


Osteoporose


De mythe: een hoge inname van melkproducten helpt tegen osteoporose beschermen.


De Nurses Health Study onderzocht specifiek de inname van melkproducten en osteoporose en vond geen bewijs dat hogere innames van melk botbreuken voorkomt. Aziatische en Afrikaanse bevolkingsgroepen onder wie lactose intolerantie de norm is en daardoor de consumptie van melkproducten minimaal of niet bestaand is, hebben veel minder mensen osteoporose dan de bevolkingsgroepen die wel melkproducten consumeren. Er zijn mensen die zeggen dat rauwe melk een gezond product is vergeleken met gepasteuriseerde melk. Het is waar dat rauwe melk enzymen bevat. Voor velen is het gemakkelijker te verteren, maar de melk in Nederland die meestal van Holstein koeien afkomstig is, heeft het probleem van BCM-7.


Dus er gaat de theorie rond, dat het drinken van melk van A1 koeien, de belangrijkste koeien die de in de Verenigde Staten voor melkproducten worden gebruikt, je blootstelt aan BCM-7 (bètacasomorfine-7), die in verband wordt gebracht met neurologische stoornissen waaronder autistische en schizofrene veranderingen. Ook diabetes type 1, een verstoorde immuunreactie, hartziekte en ook wiegendood kunnen door BCM-7 worden veroorzaakt.

Hier staat het ook allemaal nog een duidelijk beschreven:

http://www.natuurdietisten.nl/detail.php?cod=676&id=680&page=10


Van MAP (mycobacterium avium, ondersoort paratuberculosis) wordt gezegd dat deze de ziekte van Crohn en Colitis Ulcerosa veroorzaakt en deze is ook in rauwe melk aanwezig.


De nutriënten die in melk zitten, zoals calcium, fosfor en een paar vitamines, kun je gemakkelijk uit voeding of uit sommige voedingssupplementen halen. Het is slim om melk te vermijden, zelfs rauwe melk, maar als je melk wilt drinken zorg er dan voor de je melk van Holstein koeien vermijdt. Kamelenmelk is een super alternatief met vele wonderbaarlijke voordelen voor mensen met auto-immuun aandoeningen en beschadigde darmen.


Het Okinawa dieet is een goed voorbeeld. Geen melk en veel voedingsmiddelen uit de zee. Mensen met dit voedingspatroon hebben een lang leven, weinig kanker en geen degeneratieve ziekten. Een belangrijk geheim zijn de sporenelementen in hun voeding. Dat zijn er ongeveer 80 en deze zijn niet in de Westerse voeding aanwezig. Een manier om ze wel binnen te krijgen is het gebruik van Keltisch zout.


In dit forum informatie vinden